原创 03年小老头 一二学术 2022-04-22 22:22

2022年03月PubMed收录耳科学及相关研究数目从77754升至78085，增量332篇。其中影响因子十分以上论著有12篇，中国机构参与占比3/12（复旦大学Yilai Shu课题组（2篇）、山东第一医科大学Jiangang Gao课题组）。

其余该月热点论著研究还有11篇，中国机构参与占比4/11（澳门圣约瑟夫大学Raquel O. Vasconcelos课题组、台湾新竹医院Richard S. Tyler课题组、中国科学院Zhiyong Liu课题组、中国皖南医学院弋矶山医院Shaofeng Liu课题组）。

以下是该月较火研究：

1、GBD 2019 Ageing Collaborators：70岁及以上成年人的全球、地区和国家疾病和伤害负担

Title Global, regional, and national burden of diseases and injuries for adults 70 years and older: Systematic analysis for the Global Burden of Disease 2019 Study

课题组 GBD 2019 Ageing Collaborators

DOI 10.1136/bmj-2021-068208

杂志 BMJ 39.890

流行病学转变.

2、????斯托尔斯医学研究所Sungmin Baek：单细胞转录组分析揭示了斑马鱼感觉毛细胞再生过程中基因表达的三个连续阶段

Title Single-cell transcriptome analysis reveals three sequential phases of gene expression during zebrafish sensory hair cell regeneration

课题组 Tatjana Piotrowski

DOI 10.1016/j.devcel.2022.03.001

杂志 Dev Cell 12.270

3、????延世大学医学院Byunghwa Noh：体内外毛细胞基因编辑改善显性阴性Kcnq4小鼠模型的进行性听力损失

Title In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model

课题组 Jinsei Jung

DOI 10.7150/thno.67781

杂志 Theranostics11.556

4、????复旦大学Ziwen Zheng：使用基于 CRISPR/CasRx 的 RNA 编辑预防 Bth 小鼠的常染色体显性遗传性听力损失

Title Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing

课题组 Yilai Shu

DOI 10.1038/s41392-022-00893-4

杂志 Signal Transduct Target Ther 18.187

筛选用于靶向 Tmc1Bth 转录物的有效和特异性 sgRNA.

5、????威斯康星大学医学院Maryline Beurg：壁虎听觉毛细胞的非典型调谐和放大机制

Title Atypical tuning and amplification mechanisms in gecko auditory hair cells

课题组 Robert Fettiplace

DOI 10.1073/pnas.2122501119

杂志 Proc Natl Acad Sci 11.205

6、????复旦大学Xi Gu：通过体内 CRISPR/Cas9 介导的优化同源定向修复治疗小鼠常染色体隐性听力损失

Title Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice

课题组 Yilai Shu

DOI 10.1038/s41422-022-00624-y

杂志 Cell Res 25.617

7、????卡尔加里大学Marcello Tonelli, Ruth Warick：关注 COVID-19 大流行期间及以后的听力损失人群的需求

Title Focusing on the Needs of People With Hearing Loss During the COVID-19 Pandemic and Beyond

课题组 Ruth Warick

DOI 10.1001/jama.2022.3026

杂志 JAMA 56.272

8、????延世大学医学院Young Ik Koh：OSBPL2 突变会损害自噬并导致听力损失，可能通过雷帕霉素进行补救

Title OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin

课题组 Heon Yung Gee

DOI 10.1080/15548627.2022.2040891

杂志 Autophagy 16.016

9、????南特大学医院Martin Broly：THUMPD1 双等位基因变体导致 tRNA 乙酰化丧失和综合征性神经发育障碍

Title THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder

课题组 Mitchell R. O'Connell

DOI 10.1016/j.ajhg.2022.02.001

杂志 Am J Hum Genet 11.025

10、????斯坦福大学医学院Jinkyung Kim：体内实时成像显示巨蛋白作为氨基糖苷类庆大霉素转运蛋白进入耳蜗，其抑制作用具有耳保护作用

Title In vivo real-time imaging reveals megalin as the aminoglycoside gentamicin transporter into cochlea whose inhibition is otoprotective

课题组 Anthony J. Ricci

DOI 10.1073/pnas.2117946119

杂志 Proc Natl Acad Sci 11.205

11、????山东第一医科大学Xiaolong Fu：激活 Rictor/mTORC2 信号是防止感觉神经性听力损失的关键策略

Title Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss

课题组 Jiangang Gao

DOI 10.1073/pnas.2107357119

杂志 Proc Natl Acad Sci 11.205

12、???? MEE Eva Andres-Mateos：载体和手术方法的选择能够在非人灵长类动物中进行有效的耳蜗基因转移

Title Choice of vector and surgical approach enables efficient cochlear gene transfer in nonhuman primate

课题组 Luk H. Vandenberghe

DOI 10.1038/s41467-022-28969-3

杂志 Nat Commun 14.919

13、????科布伦茨大学Ibraheem Al-Dhamari：多模态耳蜗 3D 临床图像的自动主体内配准和融合

Title Automatic intra-subject registration and fusion of multimodal cochlea 3D clinical images

课题组 Stephan Waldeck

DOI 10.1371/journal.pone.0264449

杂志 PLoS One 3.240

14、????澳门圣约瑟夫大学Rafael A. Lara：噪声引起的听力损失与斑马鱼幼体内耳毛细胞减少有关

Title Noise-induced hearing loss correlates with inner ear hair cell decrease in larval zebrafish

课题组 Raquel O. Vasconcelos

DOI 10.1242/jeb.243743

杂志 J Exp Biol 3.312

15、????台湾新竹医院Alan Hsu：甲状腺功能减退症及相关共病与耳鸣风险的关系

Title Hypothyroidism and related comorbidities on the risks of developing tinnitus

课题组 Richard S. Tyler

DOI 10.1038/s41598-022-07457-0

杂志 Sci Rep 4.379

【Review】????图尔大学中心医院Luc Boullaud：内耳病理学的代谢组学研究

Title Metabolomic Studies in Inner Ear Pathologies

课题组 David Bakhos

DOI 10.3390/metabo12030214

杂志 Metabolites 4.932

16、????科隆大学Natalie Layer：单刺激人工耳蜗植入者多感官语音处理的事件相关电位研究

Title The timecourse of multisensory speech processing in unilaterally stimulated cochlear implant users revealed by ERPs

课题组 Pascale Sandmann

DOI 10.1016/j.nicl.2022.102982

杂志 Neuroimage Clin 4.881

17、????音乐媒体与技术跨学科研究中心Vincent Nadon：现场耳声发射监测评估噪声暴露对听力健康的影响

Title In Situ Otoacoustic Emission Monitoring to Assess the Effects of Noise Exposure on Hearing Health

课题组 Jérémie Voix

DOI 10.1093/annweh/wxac010

杂志 Ann Work Expo Health 2.179

18、????南卡罗来纳大学Kenneth I. Vaden：噪声中单词识别过程中皮层对感知决策标准进行调整的证据

Title Evidence for cortical adjustments to perceptual decision criteria during word recognition in noise

课题组 Mark A. Eckert

DOI 10.1016/j.neuroimage.2022.119042

杂志 Neuroimage 6.556

19、????马丁路德大学Torsten Rahne：客观听力学测试程序：适应症和鉴别诊断

Title [Objective Audiological Test Procedures: Indications and Differential Diagnostics]

课题组 Luise Wagner

DOI 10.1055/a-1673-2986

杂志 Laryngorhinootologie 1.057

20、????中国科学院Yuwei Sun：多个早期胚胎时期耳神经元谱系的单细胞转录组学景观

Title Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages

课题组 Zhiyong Liu

DOI 10.1016/j.celrep.2022.110542

杂志 Cell Rep 9.423

Graphical abstract.

21、????皖南医学院弋矶山医院Shimei Zheng：芦丁对顺铂所致耳蜗损伤的体外保护作用

Title The protective effect of rutin against the cisplatin-induced cochlear damage in vitro

课题组 Shaofeng Liu

DOI 10.1016/j.neuro.2022.03.005

杂志 Neurotoxicology 4.294

【Review】????国家科学技术研究委员会Ana Belén Elgoyhen：α9α10 烟碱型乙酰胆碱受体

Title The α9α10 nicotinic acetylcholine receptor: A compelling drug target for hearing loss?

课题组 Ana Belén Elgoyhen

DOI 10.1080/14728222.2022.2047931

杂志 Expert Opin Ther Targets 6.902

22、????斯坦福大学医学院Nicolas Grillet：扫描电子显微镜对小鼠毛细胞毛束的高分辨率成像

Title High-resolution imaging of the mouse-hair-cell hair bundle by scanning electron microscopy

课题组 Nicolas Grillet

DOI 10.1016/j.xpro.2022.101213

杂志 STAR Protoc

【Evidence-Based Primer】????新奥尔良 Ochsner 诊所Edward D. McCoul：耳鼻喉头颈外科疾病的全身性类固醇

Title Systemic Steroids for Otolaryngology-Head and Neck Surgery Disorders: An Evidence-Based Primer for Clinicians

课题组 Michael J. Brenner

DOI 10.1177/01945998221087664

杂志 Otolaryngol Head Neck Surg 3.497

23、????全南大学医学院和全南大学医院Alphonse Umugire：抗氧化剂阿文蒽酰胺-C对大剂量甲氨蝶呤所致小鼠耳毒性的影响

Title Efficiency of antioxidant Avenanthramide-C on high-dose methotrexate-induced ototoxicity in mice

课题组 Hyong-Ho Cho

DOI 10.1371/journal.pone.0266108

杂志 PLoS One 3.240

【Review】????南加州大学Patricia M. Qui?ones：在体内卸载外毛细胞束不会产生小鼠耳蜗自发振荡的证据

Title Unloading outer hair cell bundles in vivo does not yield evidence of spontaneous oscillations in the mouse cochlea

课题组 John S. Oghalai

DOI 10.1016/j.heares.2022.108473

杂志 Hear Res 3.208

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